NCT07212712 - The Role of Estrogen and Testosterone in Determining Heart, Lung, and Brain Regulation in Humans | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

March 1, 2026

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2027

Conditions

Cerebral Blood FlowCerebral Blood Flow RegulationSex DifferencesExercisePulmonaryVascular

Interventions

DRUG

GnRH antagonist

blockade of hormone production

DRUG

Estradiol (E2)

Estrogen add-back in females

DRUG

Testosterone

testosterone add-back in males

DRUG

Anastrozole (Arimidex)

Prevention of testosterone conversion to estrogen in males

Trial Locations (1)

University of British Columbia - Okanagan, Kelowna

All Listed Sponsors

lead

University of British Columbia

OTHER