NCT07211620View on ClinicalTrials.gov

KInetics of Procalcitonin to Reduce Unnecessary aNtibiotic Use - Comparing Procalcitonin Kinetics-guided Antibiotic Initiation With Using Absolute Procalcitonin Values in Reducing Unnecessary Antibiotic Use in Critically Ill Patients

NANot yet recruitingINTERVENTIONAL
Enrollment

250

Participants

Timeline

Start Date

November 30, 2025

Primary Completion Date

November 30, 2027

Study Completion Date

December 31, 2027

Conditions
InfectionSepsis
Interventions
OTHER

Kinetics

Initiation of the AB therapy is recommended for the clinician if PCT ≥ 0.5 ng/ml and PCT elevation ≥100% from the previous day's value.

OTHER

Absolute

According to the antibiotic protocol, starting ABs is recommended if PCT ≥ 0.5 ng/ml.

Trial Locations (2)

1032

Saint Margaret's Hospital, Budapest

1082

Semmelweis University, Department of Intensive Therapy, Budapest

All Listed Sponsors
lead

Semmelweis University

OTHER

NCT07211620 - KInetics of Procalcitonin to Reduce Unnecessary aNtibiotic Use - Comparing Procalcitonin Kinetics-guided Antibiotic Initiation With Using Absolute Procalcitonin Values in Reducing Unnecessary Antibiotic Use in Critically Ill Patients | Biotech Hunter | Biotech Hunter