Diagnosis Value of Interoceptive EEG Indicators by Rectal Stimulation in DoC

RecruitingOBSERVATIONAL
Enrollment

45

Participants

Timeline

Start Date

December 1, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Disorders of Consciousness
Interventions
DEVICE

Rectal Stimulation

"The stimulation balloon was lubricated with paraffin oil and inserted until the distal end of the balloon was 10 cm from the anal verge, so as to eliminate the influence of different stimulation sites on the subjects.~At the start of stimulation, the dilatable balloon was rapidly inflated to 60/80 mL, with a stimulation duration of 150 milliseconds. Concurrently with stimulation, the onset time of stimulation was marked on the electroencephalogram (EEG), and the time window for cortical potentials evoked by rapid rectal balloon distension stimulation was recorded. During the experiment, 35 stimulations were administered to the subjects; however, the first and last stimulations were excluded due to setup issues with the precision inflation-deflation control device for the intestinal balloon. Each stimulation was delivered as a 150-millisecond inflation pulse, providing 35 identical rectal stimulations. The inter-stimulus interval was randomly set to 12 ± 4 seconds, and EEG signals were"

Trial Locations (2)

230000

RECRUITING

The Second People's Hospital of Hefei, Hefei

310000

ENROLLING_BY_INVITATION

Hangzhou Normal University, Hangzhou

All Listed Sponsors
collaborator

The Second People's Hospital of Hefei

UNKNOWN

lead

YiLin Zhao

OTHER