LIRRH Trial for the Right-sided Colon Cancer

NARecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

May 1, 2025

Primary Completion Date

April 28, 2027

Study Completion Date

April 28, 2028

Conditions
Ascending Colon CancerProximal Transverse Colon Cancer
Interventions
PROCEDURE

Laparoscopic ileocecal-reconstruction right hemicolectomy (LIRRH)

The ileocolic vessels are divided at their roots, and lymph nodes of stations 203, 202, and 201 are dissected. The right colic and middle colic vessels are also divided at their roots, and the surrounding lymphatic and adipose tissue (stations 211/212/213 and 221/222/223) is cleared. The transverse colon is transected 10 cm distal to the tumor, and the ileum is divided 10 cm proximal to the ileocecal region. After tailoring the ileal mesentery, an end-to-end ileo-transverse colonic anastomosis is performed. Using a seromuscular suture, the ileum and its tailored mesentery are invaginated into the wall of the transverse colon 2 cm proximal to the anastomosis, thereby reconstructing the ileocecal valve complex.

PROCEDURE

traditional laparoscopic right hemicolectomy (TRH)

The ileocolic vessels are divided at their roots, and lymph nodes of stations 203, 202, and 201 are dissected. The right colic and middle colic vessels are likewise divided at their roots, and the surrounding lymphatic and adipose tissue (stations 211/212/213 and 221/222/223) is cleared. The transverse colon is transected 10 cm distal to the tumor, and the ileum is divided 10 cm proximal to the ileocecal junction. An end-to-side or side-to-side ileo-transverse colonic anastomosis is then performed.

Trial Locations (1)

050000

RECRUITING

The Fourth Hospital of Hebei Medical University, Shijiazhuang

All Listed Sponsors
lead

Chaoxi Zhou

OTHER