Semitendinosus Autograft vs Meniscal Allograft in Post-Meniscectomy Syndrome

NANot yet recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

September 30, 2028

Study Completion Date

September 30, 2029

Conditions
Meniscal InjuriesMeniscal TearMeniscus Lesion
Interventions
PROCEDURE

Autologous Semitendinosus Tendon Graft

Meniscal reconstruction will be performed using autologous semitendinosus tendon harvested from the ipsilateral leg. The graft diameter must be at least 6 mm. A two-tunnel fixation technique will be employed, securing the graft to the tibial plateau at the anatomic meniscal root sites. The graft will be shaped and positioned to mimic the native meniscal contour. Fibertape internal brace augmentation will be added to enhance fixation strength and graft stability. If concomitant anterior cruciate ligament reconstruction is indicated, the graft choice and ACL technique will be determined by the surgeon, without restriction. Postoperative rehabilitation will follow a standardized protocol across all centers.

PROCEDURE

Meniscal Allograft Transplantation (MAT)

Meniscal allograft transplantation will use size-matched, fresh-frozen allograft menisci prepared according to institutional tissue bank standards. Grafts will be fixed using a two-tunnel bone plug technique, restoring the anatomic root insertions. The allograft will be centrally positioned within the tibiofemoral compartment, and centralization sutures may be added at the discretion of the operating surgeon. All procedures will be standardized across participating centers, and postoperative rehabilitation protocols will be identical to those used in the autologous graft arm.

Trial Locations (1)

33305

Chang Gung memorial hospital, Taoyuan, taoyuan 333, Taoyuan

All Listed Sponsors
collaborator

Karolinska University Hospital

OTHER

lead

Chang Gung Memorial Hospital

OTHER

NCT07204587 - Semitendinosus Autograft vs Meniscal Allograft in Post-Meniscectomy Syndrome | Biotech Hunter | Biotech Hunter