NCT07203677View on ClinicalTrials.gov

Comparative Effectiveness of Tirzepatide Versus Sitagliptin in Individuals at Cardiovascular Risk (TIRZSITA-CVOT)

Active, not recruitingOBSERVATIONAL
Enrollment

49,065

Participants

Timeline

Start Date

September 19, 2025

Primary Completion Date

October 15, 2025

Study Completion Date

October 15, 2025

Conditions
Type2 Diabetes MellitusAtherosclerotic Cardiovascular Disease
Interventions
DRUG

Initiation of tirzepatide

New use of tirzepatide dispensing claim is used as the exposure.

DRUG

Initiation of sitagliptin

New use of sitagliptin dispensing claim is used as the reference.

Trial Locations (1)

02120

Brigham and Women's Hospital, Boston

All Listed Sponsors
lead

Brigham and Women's Hospital

OTHER