The Role of Janus Kinase (JAK) and Voltage-gated Sodium Channels (Nav) on Pain and Itch

NANot yet recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2026

Conditions
Itchiness
Interventions
DRUG

Delgocitinib cream

Delgocitinib cream

DRUG

lidocaine cream

Lidocaine cream

COMBINATION_PRODUCT

Lidocaine+Delgocitinib

The two cream will me mixed togheter

DRUG

Vehicle (placebo)

Vehicle Cream

OTHER

Histamine Dihydrochloride (HDC)

One drop of histamine will be applied on the selected areas and pierced with a lancet

OTHER

Cowhage (Mucuna Pruriens)

About 30 spicules will be applied on the selected areas and inserted manually

Trial Locations (1)

9260

Center for Neuroplasticity and Pain Faculty of Medicine, Aalborg University Selma Lagerløfs Vej 249 9260 Gistrup, Denmark, Gistrup

All Listed Sponsors
lead

Aalborg University

OTHER

NCT07203274 - The Role of Janus Kinase (JAK) and Voltage-gated Sodium Channels (Nav) on Pain and Itch | Biotech Hunter | Biotech Hunter