NCT07203079View on ClinicalTrials.gov

Oral Versus Intravenous Acetaminophen in Lumbar Spine Surgery

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

January 31, 2026

Primary Completion Date

October 31, 2026

Study Completion Date

January 31, 2027

Conditions
Postoperative Pain
Interventions
DRUG

Acetaminophen Oral Tablet

Participants take 1000mg by mouth every 6 hours for a total of 8 doses (48 hours total) starting within 2 hours after their spine surgery.

DRUG

placebo oral tablet

Participants take one placebo tablet (matchable to tylenol) by mouth every 6 hours for a total of 8 doses (48 hours total) starting within 2 hours after their spine surgery.

DRUG

Acetaminophen infusion

Participants take 1000mg by intravenous infusion over 15 minutes every 6 hours for a total of 8 doses (48 hours total) starting within 2 hours after their spine surgery.

DRUG

Placebo infusion

Participants take 1000mg placebo by intravenous infusion over 15 minutes every 6 hours for a total of 8 doses (48 hours total) starting within 2 hours after their spine surgery.

Trial Locations (1)

94305

Stanford University, Stanford

All Listed Sponsors
lead

Stanford University

OTHER