Quantifying Multi-step Avoidance in Anxiety

Not yet recruitingOBSERVATIONAL
Enrollment

163

Participants

Timeline

Start Date

January 31, 2027

Primary Completion Date

June 30, 2030

Study Completion Date

June 30, 2030

Conditions
AnxietyAnxiety Disorders
Interventions
BEHAVIORAL

Behavioral Tasks with imaging

"Participants will complete the MDP task only during 3 separate fMRI scanning sessions.~After each session, they will complete one week of ambulatory assessment of real-world avoidance behavior (self-reported avoidance behavior) via Emory Qualtrics surveys. In a fourth scanning session, the brain signature of threat imminence constructed in the first set of participants (Aim 1) will be used to predict and modify avoidance behavior (on the task and in a further week of ambulatory assessment of avoidance) in these participants. During their last visit, the behavioral task will be modified to decrease the availability of avoidance choices; subsequent effects on EMA and passive sensing measures will be assessed."

Trial Locations (2)

30322

Emory College, Atlanta

Facility for Education and Research in Neuroscience (FERN), Atlanta

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Emory University

OTHER