Aggressive Intravenous Hydration With or Without Indometacin to Prevent Pancreatitis After Pancreatic Extracorporeal Shock Wave Lithotripsy

NANot yet recruitingINTERVENTIONAL
Enrollment

1,250

Participants

Timeline

Start Date

December 1, 2025

Primary Completion Date

December 1, 2027

Study Completion Date

December 1, 2027

Conditions
Pancreatitis, ChronicPancreatitis, AcutePancreatic Duct Stones
Interventions
DRUG

Indometacin suppository

Administration of a 100mg indometacin suppository rectally 30 minutes prior to ESWL

DRUG

Lactated ringers solution

Intravenous 20 mL/kg Ringer's lactate solution within 60 min from the start of ESWL, directly followed by 3 mL/kg per h for 8 h.

DRUG

Normal Saline

Intravenous fluid infusion with normal saline (maximum of 1.5mL/kg per h or 3L per 24h)

Trial Locations (10)

Unknown

The Second Affiliated Hospital of Baotou Medical College, Baotou

Peking Union Medical College Hospital, Beijing

Hangzhou First People's Hospital, Hangzhou

The Third Xiangya Hospital of Central South University, Hunan

The First Hospital of Lanzhou University, Lanzhou

Qilu Hospital of Shandong University, Shandong

Changhai Hospital, Shanghai

Ruijin Hospital, Shanghai

Shanghai Pudong New Area Gongli Hospital, Shanghai

Yunnan University Affiliated Hospital, Yunnan

All Listed Sponsors
collaborator

Ruijin Hospital

OTHER

collaborator

First Affiliated Hospital of Lanzhou University

UNKNOWN

collaborator

First People's Hospital of Hangzhou

OTHER

collaborator

The Second Affiliated Hospital of Baotou Medical College

OTHER

collaborator

Shanghai Pudong New Area Gongli Hospital

OTHER

collaborator

Peking Union Medical College Hospital

OTHER

collaborator

Qilu Hospital of Shandong University

OTHER

collaborator

The Third Xiangya Hospital of Central South University

OTHER

collaborator

Affiliated Hospital of Yunnan University

OTHER

lead

Changhai Hospital

OTHER

NCT07202559 - Aggressive Intravenous Hydration With or Without Indometacin to Prevent Pancreatitis After Pancreatic Extracorporeal Shock Wave Lithotripsy | Biotech Hunter | Biotech Hunter