NCT07202000View on ClinicalTrials.gov

EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC)

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

November 1, 2025

Primary Completion Date

July 31, 2027

Study Completion Date

August 31, 2027

Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
DRUG

Activin ligand-trap biological therapy

Investigational therapy

DRUG

Placebo, Normal Saline

Inactive drug

Trial Locations (1)

02114

Massachusetts General Hospital, Boston

All Listed Sponsors
collaborator

American Heart Association

OTHER

collaborator

University of Michigan

OTHER

collaborator

Oakland University

OTHER

lead

Massachusetts General Hospital

OTHER