360
Participants
Start Date
October 8, 2025
Primary Completion Date
October 10, 2029
Study Completion Date
October 10, 2031
Mepolizumab
Subcutaneous injection of mepolizumab is administered every 4 weeks for a total treatment duration of 24 weeks.
Simple Polypectomy
Removal of nasal polyps in the middle meatus and superior turbinate region via the middle meatus and olfactory cleft, without opening the involved sinuses and without resection of diseased bone.
Extended Endoscopic Sinus Surgery
"1. Complete opening of all sinuses~2. Resection of diseased mucosa and hyperplastic bone~3. Ethmoid skeletonization with middle turbinectomy~4. Draf IIb/III frontal dissection when indicated by CT severity."
China-Japan Union Hospital of Jilin University, Changchun
The First Affiliated Hospital of Harbin Medical University, Harbin
The Second Hospital of Harbin Medical University, Harbin
Eye & ENT Hospital of Fudan University, Shanghai
Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai
Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai
The First Affiliated Hospital with Nanjing Medical University, Nanjing
The Affiliated Hospital of Qingdao University, Qingdao
Affiliated Hangzhou First People's Hospital,School of Medicine, Westlake University, Hangzhou
The First Affiliated Hospital of Fujian Medical University, Fuzhou
The First Affiliated Hospital of Chongqing Medical University, Chongqing
Renmin hospital of Wuhan University, Wuhan
The First Affiliated Hospital of Zhengzhou University, Zhengzhou
The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou
Longgang District Central Hospital of Shenzhen, Shenzhen
The Affiliated Hospital of Yunnan University, Kunming
The Second Hospital of Shanxi Medical University, Taiyuan
Eye & ENT Hospital of Fudan University
OTHER