NCT07199088View on ClinicalTrials.gov

Comparative Efficacy and Safety of Acetazolamide Versus Metolazone as an Adjunct to Standard Therapy in Patients With Acute Decompensated Heart Failure

NARecruitingINTERVENTIONAL
Enrollment

320

Participants

Timeline

Start Date

October 11, 2025

Primary Completion Date

October 16, 2026

Study Completion Date

October 30, 2026

Conditions
Acute Decompensated Heart FailureHeart Failure, DiastolicHeart Failure, Systolic
Interventions
OTHER

Acetazolamide

A carbonic anhydrase inhibitor, 500 mg orally once a day as an adjunct to loop diuretics for enhancing diuresis and improving decongestion in ADHF patients.

OTHER

Metolazone

A thiazide-like diuretic, 5 mg orally once a day as an adjunct to loop diuretics for enhancing diuresis and improving decongestion in ADHF patients.

Trial Locations (1)

Unknown

RECRUITING

Quaid e Azam Medical College , bahawalpur, Chak Eighty-seven -Twelve Left

All Listed Sponsors
lead

University of Health Sciences Lahore

OTHER