Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery

NANot yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

October 6, 2025

Primary Completion Date

December 1, 2026

Study Completion Date

May 1, 2027

Conditions
Breast CancerPain, ChronicPost Surgical Pain
Interventions
DRUG

Ketamine

"Before skin incision, a bolus 0.35 mg/kg ketamine will be given followed by a continuous infusion 0.25 mg/kg/hr.~Ketamine infusion will be stopped 30 minutes before the end of the surgery"

PROCEDURE

Pecs block

Pecs block will be performed before surgical incision with the help of an ultrasound (US) by experienced anesthesiologist. The drug used for the pecs block will be two syringes of 10ml and 20 ml containing bupivacaine 0.25% (total 30 ml).

DRUG

Nalbuphine

Intravenous Nalbuphine 0.1 mg/kg

DRUG

Paracetamol

Intravenous Paracetamol 1g or 15mg/kg (if weight is \< 50kg).

All Listed Sponsors
lead

Aga Khan University

OTHER