90
Participants
Start Date
November 1, 2025
Primary Completion Date
December 1, 2025
Study Completion Date
December 1, 2026
Sevoflurane + Remifentanil
Combination of an inhalational anesthetic (sevoflurane) and an intravenous opioid analgesic (remifentanil), both routinely used in clinical practice for maintenance of general anesthesia. These agents are administered according to standard of care, not as experimental interventions.
Propofol + Remifentanil
Combination of an intravenous anesthetic (propofol) and an intravenous opioid analgesic (remifentanil), both routinely used in clinical practice for induction and maintenance of general anesthesia. These agents are administered according to standard of care, not as experimental interventions.
Sevoflurane + Propofol + Remifentanil
Combination of an inhalational anesthetic (sevoflurane), an intravenous anesthetic (propofol), and an intravenous opioid analgesic (remifentanil). These agents are routinely used together in clinical practice for combined intravenous-inhalational anesthesia (CIVIA). All drugs are administered according to standard of care, not as experimental interventions.
Sakarya University Training and Research Hospital, Department of Anesthesiology and Reanimation, Sakarya
Sakarya University
OTHER