NCT07195006View on ClinicalTrials.gov

Early Life Malnutrition, Environmental Enteric Dysfunction and Microbiome Trajectories

RecruitingOBSERVATIONAL
Enrollment

368

Participants

Timeline

Start Date

January 27, 2025

Primary Completion Date

December 31, 2029

Study Completion Date

December 31, 2032

Conditions
Malnutrition PregnancyMalnutrition in ChildrenMalnutrition (Calorie)Environmental Enteric DysfunctionGut DysbiosisGut Permeability, Gut InflammationDiarrhea InfectiousMaternal StressChild Mental HealthNatural Killer Cell Mediated ImmunityMycotoxin BiomonitoringEnvironmental ExposuresCell-Mediated Immune Deficiency
Interventions
OTHER

Malnutrition in pregnancy as exposure

MUAC ≤23 cm in pregnancy at least 20 weeks gestational age

OTHER

Poor WASH living conditions as exposure

"Poor water (source, quality, access, reliability), sanitation (toilet type, cleanliness, number of people using toilet) and personal (hand wash practices) and household hygiene (dumpster availability and emptying frequency) index scores.~WASH Index score ranges; 1.Basic services (76-100%), 2.Semi-basic services (51-75%) 3.Poor services (26-50%) 4.No services (0-25%)"

Trial Locations (1)

Unknown

RECRUITING

University of Zimbabwe, Harare

All Listed Sponsors
collaborator

University of Bern

OTHER

collaborator

Insel Gruppe AG, University Hospital Bern

OTHER

collaborator

LMU Klinikum

OTHER

lead

University of Zimbabwe

OTHER