Comparative Real-world Study on Ablative Fractional CO₂ Laser vs PRP With Microneedling for Acne Scar Treatment.

NANot yet recruitingINTERVENTIONAL
Enrollment

116

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

September 30, 2026

Study Completion Date

November 30, 2026

Conditions
Acne ScarsAblative Fractional CO₂ Laser TherapyPlatelet-rich Plasma (PRP)
Interventions
PROCEDURE

Ablative Fractional CO₂ Laser

Participants will receive ablative fractional CO₂ laser therapy on one side of the face using the SmartXide DOT Fractionated CO₂ Laser system. Treatment parameters: 15 W power, 800 µm spacing, 600 µs dwell time, stack level 2. Sessions: 3, each one month apart.

PROCEDURE

Platelet-Rich Plasma (PRP) With Microneedling

Participants will receive intradermal autologous PRP injections prepared by double-spin centrifugation from 8 mL of venous blood, followed by microneedling with a Dermapen (12-needle cartridge, 1.5 mm depth). Endpoint: pinpoint bleeding. Sessions: 3, each one month apart.

Trial Locations (1)

Unknown

Dhala Medical College, Dhaka

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Dhaka Medical College

OTHER

lead

Dr. Sirajul Islam Medical College

OTHER