Rectal Misoprostol for Reducing Blood Loss in Elective Cesarean Section

NANot yet recruitingINTERVENTIONAL
Enrollment

282

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

October 31, 2026

Study Completion Date

December 31, 2026

Conditions
Postpartum Hemorrhage
Interventions
DRUG

Oxytocin

"Intravenous oxytocin administered per hospital protocol immediately after delivery of the baby and placenta (example regimen: 10 IU slow IV bolus followed by infusion e.g., 20 IU in 500-1000 mL isotonic crystalloid run over 2-4 hours; actual dosing adjusted per anesthesiologist/obstetrician and hospital policy). Document exact time, dose, and infusion rate in each case.~Single rectal dose of misoprostol 600-1000 µg (select dose based on patient risk profile; e.g., 600 µg for routine prophylaxis, 800-1000 µg for high-risk cases) inserted into the rectum immediately after delivery of the baby and placenta. No dilution required."

All Listed Sponsors
lead

Assiut University

OTHER

NCT07188207 - Rectal Misoprostol for Reducing Blood Loss in Elective Cesarean Section | Biotech Hunter | Biotech Hunter