Methylprednisolone vs Dexamethasone: Effects on Sugammadex Reversal, Pain, and Nausea in Adults

NANot yet recruitingINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2026

Conditions
Neuromuscular Block, ResidualPainPostoperative Nausea
Interventions
DRUG

Methylprednisolone (MP)

Methylprednisolone 1 mg/kg IV (diluted to 5 mL with saline) will be administered at induction of anesthesia. Neuromuscular blockade will be achieved with rocuronium. Reversal will be performed with sugammadex 2 mg/kg IV at the reappearance of the second twitch in train of four monitoring.

DRUG

Dexamethasone

Dexamethasone 0.2 mg/kg IV (diluted to 5 mL with saline) will be administered at induction of anesthesia. Neuromuscular blockade will be achieved with rocuronium. Reversal will be performed with sugammadex 2 mg/kg IV at the reappearance of second twitch in train of four monitoring.

Trial Locations (1)

42050

Konya City Hospital, Karatay

All Listed Sponsors
lead

Konya City Hospital

OTHER

NCT07187037 - Methylprednisolone vs Dexamethasone: Effects on Sugammadex Reversal, Pain, and Nausea in Adults | Biotech Hunter | Biotech Hunter