Evaluation of MTH in PCI Under VA-ECMO for AMICS

NANot yet recruitingINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

May 31, 2028

Study Completion Date

May 31, 2028

Conditions
Acute Myocardial Infarction Complicated With Cardiogenic ShockMild Therapeutic HypothermiaVenous-arterial Extracorporeal Membrane Oxygenation
Interventions
PROCEDURE

Mild therapeutic hypothermia

Before percutaneous coronary intervention, cooling was maintained with venous-arterial extracorporeal membrane oxygenation in patients receiving mild therapeutic hypothermia. By protocol, cooling down to the target temperature of 33°C-34°C was set at the maximum possible cooling rate. After the target temperature was reached, it was maintained for 24 hours with the temperature regulation function of the extracorporeal membrane oxygenation system by central temperature measurement in the urinary bladder. After 24 hours, rewarming was initiated with a speed of 0.25°C/h to a target temperature of 36.5℃ (± 0.3℃). To avoid shivering in the mild therapeutic hypothermia group, the patients were treated with a protocol including deep sedation and optional muscle relaxation.

All Listed Sponsors
lead

Beijing Anzhen Hospital

OTHER

NCT07186972 - Evaluation of MTH in PCI Under VA-ECMO for AMICS | Biotech Hunter | Biotech Hunter