Exploratory Trial of VR Intervention on Neuroplasticity in Older Adults With Cognitive Frailty

NAEnrolling by invitationINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

July 21, 2025

Primary Completion Date

November 30, 2025

Study Completion Date

December 31, 2025

Conditions
Cognitive Frailty
Interventions
BEHAVIORAL

VR-Based Resistance Training Intervention

"Participants in the intervention group will engage with a self-developed VR resistance training program entitled Kitten Crossing the Bridge. This program is designed to guide older adults through static lower-limb resistance exercises, while integrating rhythm control, spatial judgment, and visual feedback. The intervention will be administered over 4 weeks, with two sessions per week; each session will last approximately 20 minutes (excluding equipment setup and rest periods). All training sessions will be supervised by qualified staff to ensure participant safety and provide necessary support."

BEHAVIORAL

Standardized Leg-Raising Training

Participants in the control group will implement a standardized leg-raising exercise protocol, which is designed to match the intensity and rhythm of the VR-based intervention. Training will be guided by pre-recorded verbal prompts and demonstration videos developed by the research team, ensuring procedural uniformity. Each session will last approximately 20 minutes (excluding equipment setup and rest periods), with two sessions per week over a 4-week duration. All sessions will be supervised by trained staff, who will monitor participant adherence and ensure safety throughout the process.

Trial Locations (1)

100144

School of Nursing, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing

All Listed Sponsors
lead

Peking Union Medical College

OTHER