CD70-Targeted CAR-T Therapy in CD70-Positive Advanced Solid Tumors

PHASE1RecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

September 12, 2025

Primary Completion Date

March 31, 2028

Study Completion Date

May 31, 2028

Conditions
Renal Cell Carcinoma (RCC)Lung CancerAnaplastic Thyroid CarcinomasOvarian CancerCervical CancerThymic Carcinoma
Interventions
BIOLOGICAL

CD70-targeted CAR-T cells

Administration method: intravenous infusion. Subjects will receive conditioning therapy by Fludarabine and Cyclophosphamide before cell infusion.

BIOLOGICAL

CD70-targeted CAR-T cells

Administration method: intrapleural infusion. Subjects will receive conditioning therapy by Fludarabine and Cyclophosphamide before cell infusion.

BIOLOGICAL

CD70-targeted CAR-T cells

Administration method: intraperitoneal infusion. Subjects will receive conditioning therapy by Fludarabine and Cyclophosphamide before cell infusion.

Trial Locations (1)

230031

RECRUITING

The 901 Hospital of Joint Logistics Support Force of People Liberation Army, Hefei

All Listed Sponsors
lead

Chongqing Precision Biotech Co., Ltd

INDUSTRY