NCT07181564View on ClinicalTrials.gov

Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension

NARecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

September 11, 2025

Primary Completion Date

February 2, 2026

Study Completion Date

March 20, 2026

Conditions
Magnesium SulfateRemifentanilS 100betaS100 Beta Protein, HumanNeuron-Specific EnolaseBrain IschemiaSevoflurane AnaesthesiaPropofol/RemifentanilKetamine
Interventions
DRUG

Propofol / Remifentanil

Maintenance of general anesthesia with propofol and remifentanil; no ketamine or magnesium administered.

DRUG

Ketamine + Magnesium sulfate (drug combination)

Continuous intraoperative infusion per protocol.

DRUG

Sevoflurane and Remifentanil

Continuous intraoperative infusion per protocol.

Trial Locations (1)

26504

RECRUITING

University General Hospital of Patras, Pátrai

All Listed Sponsors
lead

University General Hospital of Patras

OTHER

NCT07181564 - Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension | Biotech Hunter | Biotech Hunter