NCT07180615View on ClinicalTrials.gov

Gut Decolonisation With Neomycin/Metronidazole or Rifaximin Before Colon Surgery

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

458

Participants

Timeline

Start Date

June 1, 2026

Primary Completion Date

January 1, 2028

Study Completion Date

June 30, 2029

Conditions
Surgical Site InfectionColon SurgerySurgical Site Infections
Interventions
DRUG

Rifaximin (Xifaxan)

Preoperative gut decolonization protocol based on oral Rifaximin 2x550mg 10 am and 10 pm on the day preceding the surgery

DRUG

Metronidazole

Preoperative gut decolonization protocols based on oral Neomycine 2x500mg and Metronidazole 2x500mg 10 am and 10pm on the day preceding the surgery

DRUG

Neomycin Sulfate

Preoperative gut decolonization protocols based on oral Neomycine 2x500mg and Metronidazole 2x500mg 10 am and 10pm on the day preceding the surgery

Trial Locations (4)

5001

Kantonsspital Aarau, Aarau

6006

Luzerner Kantonsspital, Lucerne

8063

Stadtspital Triemli, Zurich

9007

Kantonsspital St. Gallen, Sankt Gallen

All Listed Sponsors
lead

Universität Luzern

OTHER