Randomized Controlled Trial of Berberine in Combination With Doxycycline in the Treatment of Chronic Endometritis

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

206

Participants

Timeline

Start Date

March 15, 2025

Primary Completion Date

November 30, 2026

Study Completion Date

December 31, 2026

Conditions
Chronic Endometritis
Interventions
DRUG

Participants were treated with doxycycline + berberin for chronic endometritis (intervention group).

Diagnosed chronic endometritis according to endometrial biopsy pathology , the specific medication plan for the intervention group was to use doxycycline 100mg, bid + berberin 100mg, tid, continuously for 14 days.

DRUG

At present, the commonly used clinical treatment for chronic endometritis is oral doxycycline

11After hysteroscopic diagnosis of chronic endometritis, patients received monotherapy with doxycycline hydrochloride capsules for 14 days.

Trial Locations (1)

322000

RECRUITING

The Fourth Affiliated Hospital of Zhejiang University School of Medicine, Yiwu

All Listed Sponsors
lead

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

OTHER