DDAVP Effect by TEG6 in Cardiac Surgery

Not yet recruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

December 1, 2027

Study Completion Date

December 31, 2027

Conditions
Intraoperative Bleeding
Interventions
DRUG

Desmopressin after protamine reversal

"Desmopressin will be given to participants at a dose of 0.3mcg/kg after protamine reversal at the end of cardiopulmonary bypass (CPB).~Platelet function will be assessed by TEG (Thromboelastography) platelet mapping at the following points:~1. T1 TEG6s: after arterial line insertion before skin incision.~2. T2 TEG6s: after protamine (baseline function after CPB)~3. T3 TEG6s: 30 minutes after desmopressin~4. T4 TEG6s: 6 hours after (intensive care unit) ICU admission~5. T5 TEG6s: 24hours after ICU admission"

All Listed Sponsors
lead

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

OTHER

NCT07179991 - DDAVP Effect by TEG6 in Cardiac Surgery | Biotech Hunter | Biotech Hunter