Sling-Fiber Preservation POEM vs. Conventional POEM for Reducing Post-POEM GERD

NANot yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

December 1, 2025

Primary Completion Date

December 1, 2027

Study Completion Date

January 1, 2028

Conditions
Achalasia, EsophagealGERD (Gastroesophageal Reflux Disease)
Interventions
PROCEDURE

Conventional POEM

Standard posterior POEM with full-thickness myotomy, including both circular and gastric sling muscle fibers.

PROCEDURE

Sling Fiber-Preserving POEM

Posterior POEM with selective preservation of gastric sling fibers by limiting myotomy to the right of the second penetrating vessel.

Trial Locations (1)

92868

University of California, Irvine - UCI Medical Center, Orange

All Listed Sponsors
collaborator

Hoag Memorial Hospital Presbyterian

OTHER

collaborator

University of Ottawa

OTHER

collaborator

Vancouver General Hospital

OTHER

collaborator

Cedars-Sinai Medical Center

OTHER

lead

University of California, Irvine

OTHER

NCT07178821 - Sling-Fiber Preservation POEM vs. Conventional POEM for Reducing Post-POEM GERD | Biotech Hunter | Biotech Hunter