NCT07178613View on ClinicalTrials.gov

Assessment of the Dose Safety and Efficacy of Serine Combined With Fluorouracil Drugs

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

November 30, 2025

Primary Completion Date

February 28, 2026

Study Completion Date

February 28, 2026

Conditions
Advanced Colorectal Cancer
Interventions
DRUG

Serine（Oral）

"This study evaluates the dose safety and efficacy of serine in combination with fluoropyrimidine-based therapies. Primary objective: To determine the safety of oral serine administration.~Secondary objectives: 1. To assess the preliminary efficacy of serine in the study population. 2. To establish the recommended Phase 2 dose for oral serine."

DRUG

Fluoropyrimidine Drugs

"This study evaluates the dose safety and efficacy of serine in combination with fluoropyrimidine-based therapies. Primary objective: To determine the safety of oral serine administration.~Secondary objectives: 1. To assess the preliminary efficacy of serine in the study population. 2. To establish the recommended Phase 2 dose for oral serine."

All Listed Sponsors
lead

The First Affiliated Hospital of Xinxiang Medical College

OTHER