Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure

NANot yet recruitingINTERVENTIONAL
Enrollment

492

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

October 31, 2026

Study Completion Date

December 31, 2026

Conditions
Prolonged Mechanical VentilationCritical Illness
Interventions
DIETARY_SUPPLEMENT

Dietary supplement creatine

Dietary supplement creatine. The dosage of creatine will be as follows: for the first 7 days after enrolment, the daily dose will be 2x5g. From days 8 to 21, the daily dose will be 1x5g. The substance will be administered orally or through a nasogastric tube.

DIETARY_SUPPLEMENT

Dietary supplement - placebo

Dietary supplement polydextrose as a placebo. The dosage of placebo will be as follows: for the first 7 days after enrolment, the daily dose will be 2x5g. From days 8 to 21, the daily dose will be 1x5g. The substance will be administered orally or through a nasogastric tube.

OTHER

No intervention

Patients in Group 1 will serve as controls and will receive no intervention, only standard care.

Trial Locations (4)

621 00

Chronicare Mund s.r.o., Brno

639 00

Chronicare Mund s.r.o., Brno

289 24

Chronicare s.r.o., Milovice

700 30

Chronicare Nord s.r.o., Ostrava

All Listed Sponsors
lead

University Hospital Ostrava

OTHER

NCT07177183 - Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure | Biotech Hunter | Biotech Hunter