46
Participants
Start Date
October 1, 2025
Primary Completion Date
June 30, 2028
Study Completion Date
June 30, 2028
endoscopic cardia constriction ligation
The experimental group used disposable endoscopes to perform ECCL, while the control group used traditional endoscopes to perform ECCL. ECCL involves ligating and fixing the mucosa and partial muscle layer above the dentate line under direct endoscopic visualization to create folds. Post-procedure, the ligated mucosa undergoes ischemic necrosis and heals to form scar tissue, thereby reducing the cardia diameter, increasing LES pressure, and alleviating reflux symptoms.
Shenzhen Hospital of Southern Medical University, Shenzhen
Ying Zhu
OTHER