TWOSOME Trial: Single-Shot Versus Single-Tip Pulsed Field Ablation for Pulmonary Vein Isolation

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

January 24, 2023

Primary Completion Date

May 23, 2025

Study Completion Date

May 23, 2025

Conditions
Atrial Fibrillation (Paroxysmal)
Interventions
DEVICE

Pulmonary vein isolation

Pulmonary vein isolation for paroxysmal atrial fibrillation

RADIATION

cerebral magnetic resonance tomography

A subset of consecutive patients of each group (n=25 of each group) receives cMRI on the day after the procedure to asses silent cerebral lesions. A control cMRI is scheduled in case of positive findings.

DIAGNOSTIC_TEST

Biomarker assessment (C-reacitve Protein, troponine)

A subset of patients of each group (n=25 of each group) received blood tests to asses inflammation and troponine release.

Trial Locations (1)

45131

Alfried Krupp Hospital, Essen

All Listed Sponsors
lead

Alfried Krupp Krankenhaus

OTHER