The Effect of Using Octenidine Hydrochloride as a Final Irrigation Solution on Teeth With Asymptomatic Apical Periodontitis on Postoperative Pain and Treatment Success: A Prospective Randomized Clinical Study

NACompletedINTERVENTIONAL
Enrollment

142

Participants

Timeline

Start Date

March 8, 2023

Primary Completion Date

October 18, 2024

Study Completion Date

July 20, 2025

Conditions
Apical PeriodontitisPostoperative Pain
Interventions
DRUG

Octenidine dihydrochloride 0.1%

Final intracanal irrigant (aqueous solution); single administration during the final irrigation phase. Sonic activation performed in three 20-second cycles; solution refreshed with 2 mL between cycles (approximate total 6 mL per canal). Delivered through a side-vented needle positioned short of the working length.

DRUG

Chlorhexidine 2%

Final intracanal irrigant (aqueous solution); single administration during the final irrigation phase. Sonic activation performed in three 20-second cycles; solution refreshed with 2 mL between cycles (approximate total 6 mL per canal). Delivered through a side-vented needle positioned short of the working length.

Trial Locations (1)

34093

Bezmialem Vakif University Dental Hospital - Department of Endodontics, Istanbul

All Listed Sponsors
lead

Bezmialem Vakif University

OTHER