EIT vs Dynamic Compliance Guided PEEP Titration During Laparoscopic Gynecological Surgery

NANot yet recruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

September 30, 2027

Study Completion Date

October 30, 2027

Conditions
Mechanical PowerPostoperative Pulmonary Complications (PPCs)Oxygenation
Interventions
PROCEDURE

EIT-guided PEEP titration

"During the PEEP titration procedure, PEEP will be decreased from 18 cmH2O by 2 cmH2O every 20 ventilatory cycles, until a final PEEP of 6 cmH2O.~On each level of PEEP EIT parameters and Cdyn values will be recorded in both groups.~In the EIT-GROUP optimal PEEP is considered as the intersect between the lower percentage of overdistension and collapse, based on the diagnostic tool of the EIT device."

PROCEDURE

Cdyn-guided PEEP titration

"During the PEEP titration procedure, PEEP will be decreased from 18 cmH2O by 2 cmH2O every 20 ventilatory cycles, until a final PEEP of 6 cmH2O. On each level of PEEP EIT parameters and Cdyn values will be recorded in both groups.~In the Cdyn-GROUP optimal PEEP is considered as the PEEP value resulting the highest possible Cdyn measured by the ventilator."

Trial Locations (3)

1085

Semmelweis University, Budapest

2143

Flór Ferenc Hospital Kistarcsa, Kistarcsa

6400

Semmelweis Hospital Kiskunhalas, Kiskunhalas

All Listed Sponsors
collaborator

Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged

OTHER_GOV

collaborator

Semmelweis University

OTHER

lead

Pest County Flór Ferenc Hospital

OTHER

NCT07170514 - EIT vs Dynamic Compliance Guided PEEP Titration During Laparoscopic Gynecological Surgery | Biotech Hunter | Biotech Hunter