200
Participants
Start Date
October 1, 2025
Primary Completion Date
September 30, 2027
Study Completion Date
October 30, 2027
EIT-guided PEEP titration
"During the PEEP titration procedure, PEEP will be decreased from 18 cmH2O by 2 cmH2O every 20 ventilatory cycles, until a final PEEP of 6 cmH2O.~On each level of PEEP EIT parameters and Cdyn values will be recorded in both groups.~In the EIT-GROUP optimal PEEP is considered as the intersect between the lower percentage of overdistension and collapse, based on the diagnostic tool of the EIT device."
Cdyn-guided PEEP titration
"During the PEEP titration procedure, PEEP will be decreased from 18 cmH2O by 2 cmH2O every 20 ventilatory cycles, until a final PEEP of 6 cmH2O. On each level of PEEP EIT parameters and Cdyn values will be recorded in both groups.~In the Cdyn-GROUP optimal PEEP is considered as the PEEP value resulting the highest possible Cdyn measured by the ventilator."
Semmelweis University, Budapest
Flór Ferenc Hospital Kistarcsa, Kistarcsa
Semmelweis Hospital Kiskunhalas, Kiskunhalas
Kiskunhalas Semmelweis Hospital the Teaching Hospital of the University of Szeged
OTHER_GOV
Semmelweis University
OTHER
Pest County Flór Ferenc Hospital
OTHER