Computer-Aided Diagnosis for Hepatocellular Carcinoma Microvascular Invasion

RecruitingOBSERVATIONAL
Enrollment

400

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

September 1, 2026

Study Completion Date

September 1, 2027

Conditions
Hepatocellular Carcinoma (HCC)Microvascular Invasion (MVI)
Interventions
DIAGNOSTIC_TEST

Computer-Aided Diagnosis System for Preoperative Prediction of MVI in HCC

This intervention is an artificial intelligence-based computer-aided diagnosis (CAD) system developed to predict microvascular invasion (MVI) in patients with hepatocellular carcinoma using preoperative multiphase CT imaging. The system integrates deep learning, radiomics, and expert-defined imaging features to provide risk assessment and visualization of MVI prior to surgery. In this study, the CAD system will be evaluated retrospectively and prospectively in an observational manner only. The results will not influence clinical decision-making or patient management, and all treatments will follow standard of care.

Trial Locations (19)

Unknown

RECRUITING

Meng Chao Hepatobiliary Hospital of Fujian Medical University, Fuzhou

RECRUITING

Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou

RECRUITING

Zhujiang Hospital, Guangzhou

RECRUITING

Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai

RECRUITING

Zhuhai People's Hospital, Zhuhai

RECRUITING

First Affiliated Hospital of Guangxi Medical University, Nanning

RECRUITING

Guizhou Provincial People's Hospital, Guiyang

RECRUITING

Henan Provincial People's Hospital, Zhengzhou

RECRUITING

Shengjing Hospital, Shenyang

RECRUITING

West China Hospital, Chengdu

RECRUITING

Dazhou Central Hospital, Dazhou

RECRUITING

First Affiliated Hospital of Kunming Medical University, Kunming

RECRUITING

The First People's Hospital of Yunnan Province, Kunming

RECRUITING

Yunnan Cancer Hospital, Kunming

RECRUITING

First Affiliated Hospital of Wenzhou Medical University, Wenzhou

RECRUITING

Beijing Tsinghua Changgeng Hospital, Beijing

RECRUITING

Beijing YouAn Hospital, Beijing

RECRUITING

Peking Union Medical College Hospital, Beijing

RECRUITING

Eastern Hepatobiliary Surgery Hospital, Shanghai

Sponsors
All Listed Sponsors
collaborator

Peking Union Medical College Hospital

OTHER

collaborator

First Affiliated Hospital of Kunming Medical University

OTHER

collaborator

Beijing YouAn Hospital

OTHER

collaborator

Zhujiang Hospital

OTHER

collaborator

Meng Chao Hepatobiliary Hospital of Fujian Medical University

OTHER

collaborator

First Affiliated Hospital of Wenzhou Medical University

OTHER

collaborator

Fifth Affiliated Hospital, Sun Yat-Sen University

OTHER

collaborator

Henan Provincial People's Hospital

OTHER

collaborator

Guangdong Provincial Hospital of Traditional Chinese Medicine

OTHER

collaborator

Shengjing Hospital

OTHER

collaborator

Beijing Tsinghua Changgeng Hospital

OTHER

collaborator

Yunnan Cancer Hospital

OTHER

collaborator

The First People's Hospital of Yunnan

OTHER

collaborator

Guizhou Provincial People's Hospital

OTHER

collaborator

First Affiliated Hospital of Guangxi Medical University

OTHER

collaborator

West China Hospital

OTHER

collaborator

ZhuHai Hospital

OTHER

collaborator

Dazhou Central Hospital

OTHER

collaborator

Eastern Hepatobiliary Surgery Hospital

OTHER

lead

Chinese Academy of Sciences

OTHER_GOV