Microbiome and Clinical Response to Probiotics and Methotrexate in Early Psoriasis: a Pilot Study

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

August 20, 2026

Study Completion Date

December 30, 2026

Conditions
Psoriasis (PsO)
Interventions
DRUG

Probiotics and methotrexate

weekly oral methotrexate 15-25 mg/week, along with an oral daily dose of probiotics.

DRUG

Methotrexate

weekly oral methotrexate 15-25 mg/week

Trial Locations (1)

21561

RECRUITING

Medical Research Institute, Alexandria University, Alexandria

All Listed Sponsors
collaborator

Cairo University

OTHER

lead

Alexandria University

OTHER