Developing a Physiology-Pharmacodynamic Model of Rocuronium Dose and Cardiac Output to Investigate the Onset Time of Neuromuscular Relaxation

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Induction of AnaesthesiaMuscle RelaxantsRocuronium
Interventions
DRUG

Rocuronium dosing

Rocuronium doses of 0.6ng/kg, 1.2mg/kg, 1.6mg/kg and 2.0 mg/kg will be compared for onset speed of muscle relaxation and information on speed, cardiac output and patient body size entered into a computer model

All Listed Sponsors
lead

Clare Hayes-Bradley

OTHER