Visual Outcomes of an Enhanced Monofocal Intraocular Lens Targeted for Monovision in Highly Myopic Eyes: a Randomized Controlled Trial

NANot yet recruitingINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

April 1, 2026

Study Completion Date

July 1, 2027

Conditions
CataractHigh Myopia
Interventions
PROCEDURE

Enhanced monofocal intraocular lens implantation (monovision strategy)

"Participants will undergo phacoemulsification with the implantation of an enhanced monofocal intraocular lens, targeting -0.5 D in the dominant eye and -2.0 D in the non-dominant eye. The first operated eye will be selected based on the worse corrected distance visual acuity; if both eyes are similar, the eye subjectively perceived by the patient as having worse vision will be chosen. The second eye surgery will be performed within 2 weeks after the first eye surgery. Ocular dominance will be determined preoperatively using the finger method . Intraocular lens power will be calculated using multiple formulas \[Emmetropia Verifying Optical (EVO) version 2.0, Kane, LISA\]."

PROCEDURE

Enhanced monofocal intraocular lens implantation (bilateral myopia strategy)

"Participants will undergo phacoemulsification with the implantation of an enhanced monofocal intraocular lens, targeting -2.0 D in both eyes. The first operated eye will be selected based on the worse corrected distance visual acuity; if both eyes are similar, the eye subjectively perceived by the patient as having worse vision will be chosen. The second eye surgery will be performed within 2 weeks after the first eye surgery. Ocular dominance will be determined preoperatively using the finger method. Intraocular lens power will be calculated using multiple formulas \[Emmetropia Verifying Optical (EVO) version 2.0, Kane, LISA\]."

All Listed Sponsors
collaborator

Shenzhen Eye Hospital

OTHER

lead

Zhongshan Ophthalmic Center, Sun Yat-sen University

OTHER

NCT07168109 - Visual Outcomes of an Enhanced Monofocal Intraocular Lens Targeted for Monovision in Highly Myopic Eyes: a Randomized Controlled Trial | Biotech Hunter | Biotech Hunter