150
Participants
Start Date
September 15, 2025
Primary Completion Date
December 31, 2026
Study Completion Date
December 31, 2026
semaglutide combined with metformin
The initial dose of semaglutide is 0.25 mg once weekly. After 4 weeks, the dose is adjusted to 0.5 mg once weekly. After another 4 weeks, the dose is adjusted to 1 mg once weekly. During the same period, they will take metformin (500mg each time, three times a day) for treatment. The treatment course is 12 months.
The First Affiliated Hospital of Xiamen University, Xiamen
Peking University First Hospital
OTHER
Shanghai Punan Hospital of Pudong New District
OTHER
Shanghai 6th People's Hospital
OTHER
Jinzhou Medical University
OTHER
The First Affiliated Hospital of Xiamen University
OTHER