Serratus Posterior Superior Plane Block for Postoperative Pain in Cardiac Surgery

NARecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

September 13, 2025

Primary Completion Date

February 1, 2026

Study Completion Date

April 1, 2026

Conditions
Cardiac SurgeryPost Operative Pain, Acute
Interventions
PROCEDURE

Bilateral ultrasound guided Serratus Posterior Superior Plane Block

Bilateral ultrasound-guided Serratus Posterior Superior Plane Block (total of 60 ml, %0.25 bupivacaine) will be performed Multimodal analgesia : Intraoperatively, all patients will receive 0.05 mg/kg (IBW) iv morphine. Thirty minutes before the end of surgery, 1 gram of intravenous paracetamol will be administered. Postoperative analgesia: iv paracetamol 1gr every 8 hours and IV PCA of 0,5mg/ml morphine. In cases where rescue analgesia is required (NRS score ≥4),iv fentanyl 25-50 mcg and/or ibuprofen and/or ketamine 10 mg will be administered. Patients are routinely administered iv dexamethasone 4 mg and IV 8 mg ondansetron 20 minutes before end of surgery for postoperative nausea and vomiting prophylaxis.

DRUG

IV morphine patient-controlled analgesia

IV PCA of 0,5mg/ml morphine (the bolus dose is 20 μg/kg, the lock-in time of 6-10 minutes, the 4-hour limit is adjusted to be 80% of the calculated total amount).

PROCEDURE

Bilateral ultrasound guided Sham Block

"Bilateral ultrasound-guided needle placement will be performed in the same anatomical plane as in the SPSIP group, but instead of local anesthetic, an equivalent volume of normal saline (30 mL per side) will be injected.~Multimodal analgesia : Intraoperatively, all patients will receive 0.05 mg/kg (IBW) iv morphine. Thirty minutes before the end of surgery, 1 gram of intravenous paracetamol will be administered. Postoperative analgesia: iv paracetamol 1gr every 8 hours and IV PCA of 0,5mg/ml morphine. In cases where rescue analgesia is required (NRS score ≥4),iv fentanyl 25-50 mcg and/or ibuprofen and/or ketamine 10 mg will be administered. Patients are routinely administered iv dexamethasone 4 mg and IV 8 mg ondansetron 20 minutes before end of surgery for postoperative nausea and vomiting prophylaxis."

Trial Locations (1)

55270

RECRUITING

Burhan Dost, Samsun

All Listed Sponsors
lead

Ondokuz Mayıs University

OTHER

NCT07164677 - Serratus Posterior Superior Plane Block for Postoperative Pain in Cardiac Surgery | Biotech Hunter | Biotech Hunter