Tragus Stimulation for POTS Treatment

NANot yet recruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

January 31, 2027

Conditions
Postural Orthostatic Tachycardia Syndrome (POTS)
Interventions
DEVICE

Transcutaneous auricular vagus nerve stimulation

"Transcutaneous auricular vagus nerve stimulation (tVNS) is an emerging therapeutic modality in cardiovascular diseases. tVNS has been shown to exert antiadrenergic and anti-inflammatory effects in humans. Recently, tVNS has been tested in experimental and human POTS, leading to improved autonomic function, reduction of anti-autonomic autoantibodies and inflammatory cytokines.~Parasym device; Parasym Health, London, United Kingdom Frequency: 20Hz, pulse width: 200μs, amplitude will be individually titrated to 1 mA below the level that caused mild discomfort."

All Listed Sponsors
lead

Aristotle University Of Thessaloniki

OTHER