Guiding Fluid Resuscitation in Septic Shock: Ultrasound vs. Noninvasive Cardiac Output Monitoring

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

July 5, 2023

Primary Completion Date

July 31, 2025

Study Completion Date

July 31, 2025

Conditions
Septic Shock
Interventions
DEVICE

non-invasive cardiac output monitoring

Monitoring commenced immediately after enrollment, with baseline parameters recorded after signal stabilization (≤5 minutes), including cardiac output (CO), stroke volume (SV), stroke volume variation (SVV), and systemic vascular resistance (SVR). The system automatically updated these parameters every 30 seconds and displayed them in real-time on the monitor screen. Fluid resuscitation was dynamically adjusted according to these continuous measurements until achieving the predefined therapeutic targets.

DEVICE

Ultrasonic technology

In the critical care ultrasound group, patients underwent immediate bedside This protocol ensured real-time, comprehensive evaluation of both cardiac function and fluid status to guide resuscitation.Ultrasound reassessment was performed every 1-2 hours to dynamically adjust both the volume and rate of fluid administration until predefined resuscitation targets were achieved.

Trial Locations (1)

510000

Panyu Central Hospital Affiliated to Guangzhou Medical University, Guangzhou

All Listed Sponsors
collaborator

Guangzhou Panyu Central Hospital

OTHER

lead

Mai Xiaowei

OTHER