Ganglion Resection Effectiveness Trial

NANot yet recruitingINTERVENTIONAL
Enrollment

220

Participants

Timeline

Start Date

November 30, 2025

Primary Completion Date

December 31, 2034

Study Completion Date

December 31, 2035

Conditions
Wrist GanglionGanglionGanglion CystConnective Tissue DiseaseMucinoses
Interventions
PROCEDURE

Open resection

A transverse or longitudinal incision is done depending on surgeon's preference. The ganglion and its pedicle are traced up to its origin. The pedicle is resected tangentially, usually, from the SL ligament for dorsal ganglions and depending on the site for volar ganglion. Wrist capsule is not closed.

PROCEDURE

Arthroscopic resection

Portals are selected by surgeon's preference. The pedicle of the ganglion is located and resected with a shaver. It is not necessary to remove all the ganglion walls. The portal incisions do not need to be sutured.

OTHER

Conservative treatment

Participant will be informed about the natural course of wrist ganglions. The conservative treatment may include needle aspiration of the ganglion, but it is not performed routinely. Participants are informed that wrist loading in extension may exacerbate the pain, and that the pain is not a sign of further injury to wrist joint. They can avoid heavy use it if they have too much pain, but they are advised to use hand as tolerated. Participants may use NSAIDs and acetaminophen for pain management as needed; however, the protocol does not specify a required course or dosage. A simple self-implemented exercise therapy instructions are given to every participant.

Trial Locations (4)

33521

Tampere University Hospital, Tampere

40620

Hospital Nova of Central Finland, Jyväskylä

119228

National University Hospital, Singapore

00029

Helsinki University Hospital, Helsinki

All Listed Sponsors
collaborator

Tampere University

OTHER

collaborator

Hospital Nova of Central Finland

UNKNOWN

collaborator

National University Hospital, Singapore

OTHER

collaborator

Helsinki University Central Hospital

OTHER

lead

Tampere University Hospital

OTHER

NCT07162415 - Ganglion Resection Effectiveness Trial | Biotech Hunter | Biotech Hunter