NCT07162194View on ClinicalTrials.gov

MRI-Based Machine Learning Approach Versus Radiologist MRI Reading for the Detection of Prostate Cancer, The PRIMER Trial

NARecruitingINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

September 19, 2025

Primary Completion Date

October 15, 2027

Study Completion Date

October 15, 2028

Conditions
Prostate Carcinoma
Interventions
PROCEDURE

Digital Rectal Examination

Undergo DRE

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI/TRUS

PROCEDURE

Pathologic Examination

Undergo prostate tissue mapping and evaluation using a special mold

PROCEDURE

Targeted Prostate Biopsy

Undergo targeted prostate biopsy based on PIRADS

PROCEDURE

Targeted Prostate Biopsy

Undergo targeted prostate biopsy using GL AI predictions

PROCEDURE

Targeted Prostate Biopsy

Undergo targeted prostate biopsy using DL AI predictions

PROCEDURE

Transrectal Ultrasound

Undergo MRI/TRUS

Trial Locations (1)

90033

RECRUITING

USC / Norris Comprehensive Cancer Center, Los Angeles

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

University of Southern California

OTHER

NCT07162194 - MRI-Based Machine Learning Approach Versus Radiologist MRI Reading for the Detection of Prostate Cancer, The PRIMER Trial | Biotech Hunter | Biotech Hunter