Combined tDCS and Cognitive Training as an Adjunctive Treatment in Opioid Use Disorder

NANot yet recruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

November 1, 2025

Primary Completion Date

August 1, 2026

Study Completion Date

August 1, 2026

Conditions
Opioid Use DisorderBuprenorphine
Interventions
DEVICE

Transcranial Direct Current Stimulation (tDCS)

We will deliver 2-mA tDCS current intensity during a 30 minute stimulation period (including a 30-second ramp-up and 30-second ramp-down period) to the dorsolateral prefrontal cortex. Electrodes will be fixed on marked locations based on the 10-20 EEG system. Anodal stimulating electrode will be over the left DLPFC (F3) and cathodal electrode over the right DLPFC (F4).

DEVICE

Sham Stimulation

electrodes will have the same montage as active tDCS (F3/F4), but current will be ramped down after the initial 30 seconds ramp-up period. Thus, participants will feel the initial sensation associated with tDCS but will receive no active current for the rest of the stimulation period.

Trial Locations (1)

55455

University of Minnesota, Minneapolis

All Listed Sponsors
lead

University of Minnesota

OTHER

NCT07158853 - Combined tDCS and Cognitive Training as an Adjunctive Treatment in Opioid Use Disorder | Biotech Hunter | Biotech Hunter