Effect of ORI-guided Oxygen Titration on Oxidative Stress in Rhinoplasty Surgery

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

March 1, 2021

Primary Completion Date

August 20, 2021

Study Completion Date

August 30, 2021

Conditions
RhinoplastyOxidative StressHyperoxiaOxygen Reserve Index
Interventions
DEVICE

FiO₂ titration, under the guidance of ORI

In Group R, FiO₂ was titrated between 30% and 50% under the guidance of ORI and SpO₂ values. Accordingly, if SpO₂ was ≥ 98%, FiO₂ was reduced in 5% increments to a minimum of 30%, aiming to achieve an ORI value of 0 or as close to 0 as possible.

DEVICE

Conventional oxygen administration

In Group C, FiO₂ was maintained at 50% throughout the surgery, provided that SpO₂ remained ≥ 98%.

Trial Locations (1)

34862

Kartal Dr. Lütfi Kırdar City Hospital, Istanbul

All Listed Sponsors
lead

Dr. Lutfi Kirdar Kartal Training and Research Hospital

OTHER_GOV

NCT07158073 - Effect of ORI-guided Oxygen Titration on Oxidative Stress in Rhinoplasty Surgery | Biotech Hunter | Biotech Hunter