1,546
Participants
Start Date
September 29, 2025
Primary Completion Date
November 1, 2027
Study Completion Date
December 1, 2027
tranexamic acid
In patients assigned to tranexamic acid, 2.0 g dissolved in 50 ml of 0.9% saline）will be given intravenously within 30 mins after skin incision.
0.9 % saline
In patients assigned to placebo, a comparable volume of 0.9% saline will be given.
West China Hospital
OTHER
The Affiliated Hospital of Qingdao University
OTHER
The First Affiliated Hospital of Zhengzhou University
OTHER
Huashan Hospital
OTHER
Tianjin First Central Hospital
OTHER
The First Hospital of Jilin University
OTHER
Third Affiliated Hospital, Sun Yat-Sen University
OTHER
First Affiliated Hospital, Sun Yat-Sen University
OTHER
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
OTHER
The First Affiliated Hospital with Nanjing Medical University
OTHER
Tongji Hospital
OTHER
People's Hospital of Guangxi Zhuang Autonomous Region
OTHER
The First Affiliated Hospital of University of Science and Technology of China
OTHER
The First Affiliated Hospital of Anhui Medical University
OTHER
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
OTHER
First Affiliated Hospital Xi'an Jiaotong University
OTHER
Fujian Medical University Union Hospital
OTHER
First Affiliated Hospital of Guangxi Medical University
OTHER
Second Affiliated Hospital of Guangzhou Medical University
OTHER
Zhejiang University
OTHER
Hebei Medical University Third Hospital
OTHER
Shandong First Medical University
OTHER
Nanjing Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University
UNKNOWN
RenJi Hospital
OTHER