Perioperative Nutrition Optimization for Reducing Complications After Surgical Fracture Fixation

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

1,000

Participants

Timeline

Start Date

January 1, 2026

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2027

Conditions
Lower Extremity Fracture
Interventions
DIETARY_SUPPLEMENT

CEAA supplementation

(including calcium beta-hydroxy-beta- methylbutyrate monohydrate, L-Arginine, L-Glutamine and Ciltruline) Supplementation will be started within 72 hours of presentation and continued for a period of 28 days.

OTHER

Placebo

a neutral powder containing the non- essential amino acid Alanine which will be indistinguishable from the CEAA supplement powder in in regards to packaging and supplement appearance.

All Listed Sponsors
lead

University of Minnesota

OTHER