Efficacy Of Combined Microneedling Plus Tretinoin In Treatment Of Stria Rubra

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

September 5, 2025

Primary Completion Date

November 30, 2025

Study Completion Date

September 5, 2026

Conditions
Striae
Interventions
PROCEDURE

Micro needle injection

"* Disinfection: the affected area by alcohol 70 %.~* Topical anaesthetic cream will be applied: pridocaine (lidocaine 2.5% and prilocaine 2.5%) for 30 minutes under occlusion.~* Microneedling with tretinoin 0.025% of the affected area will be done by dermapen that will be applied on the affected area as follows: inserting the sterilized needle into the dermapen tip, turning on using speed setting and adjusting speed on 5, needle depth of dermapen will be adjusted to (2- 2.5mm) according to the site of the striae, passing vertically over the striae with dermapen in a stamping pattern until pin point bleeding appear."

PROCEDURE

Micro needle injection only

"* Disinfection: the affected area by alcohol 70 %.~* Topical anesthetic cream will be applied: pridocaine (lidocaine 2.5% and prilocaine 2.5%) for 30 minutes under occlusion.~* Microneedling with timolol 0.5% of the affected area will be done by derma pen that will be applied on the affected area as follows: inserting the sterilized needle into the derma pen tip, turning on using speed setting and adjusting speed on 5, needle depth of derma pen will be adjusted to (2- 2.5mm) according to the site of the striae, passing vertically over the striae with derma pen in a stamping pattern until pin point bleeding appear."

All Listed Sponsors
lead

Sohag University

OTHER