TREATMENT OF VAGINAL DRYNESS IN SJÖGREN'S DISEASE WITH CO2-LASER VERSUS TOPICAL PROMESTRIENE

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

January 19, 2026

Primary Completion Date

August 20, 2029

Study Completion Date

December 30, 2029

Conditions
Sjogren SyndromeSjogren DiseasePrimary Sjogren Syndrome
Interventions
DEVICE

Fractional CO2 laser (vaginal)

Vaginal fractional CO2 laser applications will be performed once a month for three consecutive months.

DRUG

Promestriene Vaginal

Patients in the group treated with promestriene will apply a 10 mg vaginal capsule at night for fifteen consecutive days and, after this period, one application every three days, until completing six months of treatment.

All Listed Sponsors
collaborator

Fundação de Amparo à Pesquisa do Estado de São Paulo

OTHER_GOV

lead

University of Sao Paulo General Hospital

OTHER