Influence of Original Native Mitral Valve Lesion (Stenosis or Steno-insufficiency vs. Insufficiency) on Post-implant Structural Bioprosthetic Degeneration After Mitral Valve Replacement

Enrolling by invitationOBSERVATIONAL
Enrollment

3,500

Participants

Timeline

Start Date

January 1, 2024

Primary Completion Date

November 1, 2025

Study Completion Date

May 1, 2026

Conditions
Degeneration Mitral Bioprosthesis
Interventions
PROCEDURE

Mitral valve replacement

"All operations were performed through median longitudinal sternotomy or mini-sternotomy.~Intraoperative transesophageal echocardiography (TOE) was used in all patients. Arterial cannulation was central and venous cannulation was achieved with a common two-stage cannula in the right atrium. Left ventricle was vented through the right superior pulmonary vein. In minimally invasive procedures, venous cannulation was achieved percutaneously. Myocardial protection was achieved by administration of cold crystalloid or blood cardioplegia at the surgeon's discretion in an antegrade (indirect or selective) or retrograde fashion. The removal of the calcified cusps and the decalcification of the annulus was performed according to traditional techniques. All the prosthesis were be implanted with supranular technique and 2-0 U-shaped pledgeted sutures."

Trial Locations (1)

Unknown

Maastricht UMC+, Maastricht

All Listed Sponsors
lead

Maastricht University Medical Center

OTHER